LONG-RANGE EPISTASIS MEDIATED BY STRUCTURAL CHANGE IN A MODEL OF LIGAND BINDING PROTEINS.

Recent analyses of amino acid mutations in proteins reveal that mutations at many Latest Product Releases & Innovations – Stay Updated! pairs of sites are epistatic-i.e., their effects on fitness are non-additive-the combined effect of two mutations being significantly larger or smaller than the sum of their effects considered independently.Inter

Abstract Background Pakistan has high maternal mortality, particularly in the rural rubbermaid 8 gallon trash can areas.The delay in decision making to seek medical care during obstetric emergencies remains a significant factor in maternal mortality.Methods We present results from an experimental study in rural Pakistan.Village clusters were random